DIFFERENCES OF MASS AND DIAMETER MUSCLE RATTUS NORVEGICUS IN GIVING KETOGENIC DIETS AND EXERCISE

Abstract

Introduction: Saturated ketogenic diet without exercise can lead to muscle mass decreaseand disturb body metabolism. Therefore, the researcher is interested in discovering thedifferences between a saturated and unsaturated ketogenic diet with exercise to muscle massand diameter.
Purpose: This study aimed to analyze the difference in muscle mass and diameter of Rattusnorvegicus, which were given a ketogenic diet and exercise.
Method: This experimental research used Rattus norvegicus that had been adapted for twoweeks. Rats are divided into five groups; control (K), a saturated ketogenic diet (P1), asaturated ketogenic diet with exercise (P2), an unsaturated ketogenic diet (P3), and an
unsaturated ketogenic diet with exercise (P4). Upright running wheel exercise was given tothe group with exercise for 10 minutes daily. The ketogenic diet was given with oral gavage.Muscle mass was examined in the second and fourth weeks. Muscle diameter was examinedbefore treatment, second week, and fourth week.
Results: There are differences in mass and diameter muscle Rattus norvegicus that given
ketogenic diet and exercise (p=0,000). In second week, there are significant increase in
muscle diameter for saturated ketogenic diet without exercise (P1(p=0,000)) and significant
decrease in muscle diameter for three other group (P2(p=0,000), P3(p=0,001), P4(p=0,000)).In the fourth week, there is a significant increase in muscle diameter for an unsaturatedketogenic diet with exercise (P4).
Conclusion: An unsaturated ketogenic diet with exercise could increase the mass and
diameter of quadriceps muscle at the end of this research.