Uric Acid Concentration With Risk Factors For Hypertensionwith Coronary Heart Disease Patients Who Do Moderaty Intensity Physical Exercise

Nindya Amalia, Sianty Dewi, Dyana Sarvasti

Abstract


Introduction: Complication of hypertension causes 45% of deaths from heart disease. Programs for improving quality of life in heart disease patients such as Cardiovascular Prevention and Rehabilitation program, usually includes one component, which is to do moderate-intensity physical exercise. previous study suggested that moderate-to-high intensity physical exercise could increase uric acid. Aim: To examine the correlation between uric acid concentration and risk factors for hypertension in patients with coronary heart disease who do moderate intensity physical exercise. Method: This was a retrospective study using data from medical records with cross-sectional design. The sampling method used purposive sampling based on subjective consideration and the availability of certain criteria. Analysis used chi-square analysis Results: The data were taken from medical records from 2012 until July 2019. Sampling, which appropriates for inclusion and exclusion criteria in Husada Utama Hospital, was 30 samples, 25 male, and 5 female. The majority of subjects in this research was 56-65 years old. The youngest was 40 years old while the oldest was 77 years old. Data analysis results showed that patients who had hypertension risk factors and increased uric acid were 17 patients (85%) and who did not have hypertension risk factors1. They did not experience an increase were seven people (70%) from the chi-square test. significant with p = 0.003 (p<0.05). Conclusion: There is a significant correlation between uric acid concentration and risk factors for hypertension in patients with coronary heart disease who do moderate-intensity physical exercise.

Full Text:

PDF

References


Kemenkes RI. Situasi kesehatan jantung. Pusat data dan informasi kementerian kesehatan RI. 2014. P 3. Available from: http://www.depkes.go.id/download.php?file=download/pusdatin/infodatin/infodatin-jantung.pdf

Smith SC, Benjamin EJ, Bonow RO, Braun LT, Creager MA, Franklin BA, et al. AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update. J Am Coll Cardiol. 2011;58(23):24322446. Available from: https://depts.washington.edu/uwmedres/pdf/articles/2011%20AHA%20secondary%20prevention%20guidelnes.pdf

Ades PA, Balady GJ, Franklin BA, Yancy CW, Gordon NF, Bittner VA, et al. Referral, enrollment, and delivery of cardiac rehabilitation/secondary prevention programs at clinical centers and beyond. Circulation. 2011;124(25):29512960. Available from: https://pdfs.semanticscholar.org/1566/3da7547853496ffc7cf700586e9ae2b5465d.pdf

Schmid J-P, Wood D, Carre F, Benzer W, McGee H, Mendes M, et al. Secondary prevention through cardiac rehabilitation: physical activity counselling and exercise training: Key components of the position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Eur Heart J. 2010;31(16):19671974. Availablefrom: https://pdfs.semanticscholar.org/621f/aaa83bf3144402f8c4b49ebb532a3880a7e0.pdf

Franklin BA, Lavie CJ, Squires RW, Milani R V. Exercise-based cardiac rehabilitation and improvements in cardiorespiratory fitness: implications regarding patient benefit. Mayo Clin Proc. 2013;88(5):431437. Available from: https://www.mayoclinicproceedings.org/article/S0025-6196(13)002255/pdf

Wibisono E, Susilo A, Nainggolan L. Kapita Selekta Kedokteran. 4th ed. Tanto C, Liwang F, Hanifati SPE, editor. Media Aesculapius. 2014.

Saner H, Mcgee H, Hellemans I, Monpere C. Cardiovascular prevention and rehabilitation. London: Springer; 2007.

Kusumadewi F, Sumekar TA. Hubungan antara intensitas aktivitas fisik dan kadar asam urat serum pada populasi sindrom metabolik. Kedokteran, Univ Diponegoro. 2015;4(4):723731. Available from: https://ejournal3.undip.ac.id/index.php/medico/index

Robiyatul H. Hubungan antara peningkatan kadar asam urat darah dengan kejadian hipertensi di RSUD Sukoharjo. Skripsi Universitas Muhammadiyah Surakarta; 2015. Available from: http://eprints.ums.ac.id/39488/17/NASKAH%20PUBLIKASI.pdf

Johnson RJ, Kang DH, Feig D, Kivlighn S, Kanellis J, Watanabe S, et al. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? Hypertension. 2003;41(6):11831190. Available from: https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.0000069700.62727.C5

Boccatonda A., Tripaldi R., Dav G., Santilli F. Oxidative stress modulation through habitual physical activity. Curr Pharm Des., 22: 3648-3680, 2016. Available from: https://serval.unil.ch/resource/serval:BIB_7F872FE8DF7C.P001/REF

Chevion S, Moran DS, Heled Y, Shani Y, Regev G, Abbou B, et al. Plasma antioxidant status and cell injury after severe physical exercise. Proc Natl Acad Sci. 2003;100(9):51195123. Available from: https://pdfs.semanticscholar.org/1677/5029e1b7faec7d94dbc118d98d9c3d3d87b9.pdf

Deaton CM, Marlin DJ Exercise associated oxidative stress. Clin Tech Equine Prac 2003;2(3),2782791. Available from: https://www.sciencedirect.com/journal/clinical-techniques-in-equinepractice

Meisinger C, Koenig W, Baumert J, Dring A. Uric acid levels are associated with all-cause and cardiovascular disease mortality independent of systemic inflammation in men from the general population the MONICA ORA cohort study. Arterioscler Thromb Vasc Biol. 2008;28(6):11861192. Available from: https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.107.160184

Radi B, Joesoef AH, Kusmana D. Rehabilitasi Kardiovaskular Di Indonesia. 2009;30(2):435. Available from: http://ijconline.id/index.php/ijc/article/download/162/165/

Kementerian Kesehatan Republik Indonesia. Hasil Riset Kesehatan Dasar Kementerian RI 2013. Proceedings, Annu Meet - Air Pollut Control Assoc [Internet]. 2013;6. Available from: http://www.depkes.go.id/resources/download/general/Hasil Riskesdas2013.pdf

Murray RK, Granner DK, Mayes PA, Rodwell VW. Harpers Illustrated Biochemistry (31st Edition). Biochemical Education. 2018.

InfoDATIN. Mencegah dan mengontrol hipertensi agar terhindar dari kerusakan organ jantung. Pusat Data dan Informasi Kementerian Kesehatan RI. 2014;3-4.

Sargowo D. Patogenesis aterosklerosis. Malang: UBPress, 2015. P 298




DOI: https://doi.org/10.33508/jwmj.v2i3.2664

Refbacks

  • There are currently no refbacks.




Creative Commons License
Journal of Widya Medika Junior is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License