Staphylococcus Aureus Colonization On An Erythrodermic Psoriasis Patient

Dave Gerald Oenarta, NN Sri Budayanti, NN Dwi Fatmawati, NM Adi Tarini


Skin plays an important role as the physical barrier and first-line immunological defense against dangerous stimuli, including bacteria. Erythroderma is a condition of excessive skin irritation causing extensive erythema and desquamation. Erythroderma itself is caused by various underlying conditions, one of them is psoriasis vulgaris. In erythroderma, there is an extensive disruption of physical barrier leading to the exposure of various bacteria, including Staphylococcus aureus. In human, this bacteria can either colonize or infect the host if exposed to open wound. It is essential to determine this as it will affect the necessity of administering antibiotics. Laboratory examinations such as complete blood count, Gram staining, and culture can help to determine the status of this bacteria. A correlation between clinical features and laboratory examinations is paramount in deciding patient management.

Save to Mendeley


Staphylococcus Aureus, Erythroderma, Physical Barrier, Colonization, Pathogen

Full Text:



Alonzo, F., Torres, V.J., 2013. A Lesson in Survival: S. aureus versus the Skin. Cell Host Microbe 13, this issue, p 3-5.

Sehgal, V.N., Srivastava,G., Sardana, K. 2004. Erythroderma/exfoliative dermatitis: a synopsis. International Journal of Dermatology (43) p 39–47.

Umar, S.H., Elston,D.M., 2014. Erythroderma (Generalized Exfoliative Dermatitis).Available on: Accessed: 28th October 2015.

Liu, G.Y., 2009. Molecular Pathogenesis of Staphylococcus aureus Infection. Pediatr Res 65 (5 pt 2) p 71-77.

Zattra, E., Fortina, A.B., Peserico, A., 2012. Erythroderma in the era of biological therapies. Eur J Dermatol 22: (2), p167-71.

Teran, C.G.; Teran, C.N.; Balderrama, C. 2010. A severe case of erythrodermic psoriasis associated with advanced nail and joint manifestations: a case report. Journal of Medical Case Reports 4:1794:(179) p 1-3.

Byer, R.L; Bachur, R.G. 2006. Clinical deterioration among patients with fever and erythroderma. Pediatrics (6) p 2450-2460.

Zuel-Fakkar, N.M., El-Shokry,M.H. 2010. Study of Erythroderma and Psoriasis Exacerbation by Staphylococcal Superantigens. J Egypt Women Dermatol Soc 7: p 123 - 128.

Coates, R., Moran, J., Horsburgh, M.J., 2014. Staphylococci: colonizers and pathogens of human skin. Future Microbiol. 9(1) : p 75-91

Forbes, B.A., Sahm, D.F., Weissfeld, A.S., 2007. Staphylococcus, Micrococcus, and similar organism, In: Bailey & Scott’s Diagnostic Microbiology. 12th ed. Missouri: Mosby Elsevier:p 254-263.

Otto, M., 2010. Staphylococcus colonization of the skin and antimicrobial peptides. Expert Rev Dermatol 5(2): 183–195

Tong, S.Y.C, Davis, J.S; Eichenberger, E.; Holland, T.L.; Fowler, V.G. 2015. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management. Clin Microbiol Rev (28) p 603-635.