MICROBIOLOGICAL ASPECT OF STAPHYLOCOCCAL INFECTION IN SEVERE DEGREE OF BURNS

Venny Tandyono

Abstract


Introduction: Burns serve as one of the most common devastating forms of trauma. Significant thermal injuries induce skin disruption and immunosupression that predispose patients to infectious complication. The importance of sampling, detection, and proper treatment for wound infections will significantly increase the likelihood of clinical improvement of the patients. Case: A 44-years-old male came to hospital due to electrical shock. There were serious burns to his face, chest, arms, and legs, some of which were second- and third-degree burns. The patient was conscious, without problems on airway and breathing. Leukocytosis with neutrophilia was presented from laboratory examination, with an increase in liver enzymes and serum creatinine. The gram-positive cocci with leucocytes were revealed from gram examination, and colonization of Staphylococcus aureus was found. Intravenous cefazolin was administered according to the sensitivity test. Discussion: Infection causes the increase in morbidity and mortality of burn patients. Clinical diagnosis of infection must be supported microbiologically by gram examination and culture. One of the most common infectious agents in severe burns is Staphylococcus aureus. The significance of S.aureus as the leading cause of infection must be supported by microbiological data. Dominant growth in culture media and induction of host inflammatory response were indicated as significance of infection. Conclusion: Clinical and microbiological diagnosis of burns infection play important role to prevent complications in severe degree of burns.

Save to Mendeley


Keywords


Staphylococcus aureus, Burns, Microbiology, Antibiotics

Full Text:

PDF

References


Grace, Pierce A. & Borley, Neil R. At a Glance Ilmu Bedah. Edisi ketiga. Jakarta: Erlangga. Kapita selekta; 2006

Murray CK in Bennet JE, Dolin R, Blaser MJ. Principles and Practice of Infectious Disease: Burns. 8th edition. Philadelphia: Elsevier; 2015

Robert, Lauren in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Specimen Collection and Processing. Fifth edition. United States: Saunders; 2015

Mahon CR in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Microscopic Examination of Materials from Infected Sites. Fifth edition. United States: Saunders; 2015

Monson LS in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Staphylococci. Fifth edition. United States: Saunders; 2015

Lehman DC, Mahon CR, Suvarna K in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Streptococcus, Enterococcus, and Other Catalase-Negative, Gram-Positive Cocci. Fifth edition. United States: Saunders; 2015

Manuselis G, Mahon CR in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Use of Colony Morphology for the Presumptive Identification of Microorganisms. Fifth edition. United States: Saunders; 2015

Que Yok-Ai, Moreillon P in Bennet JE, Dolin R, Blaser MJ. Principles and Practice of Infectious Disease: Staphylococcus aureus (Including Staphylococcal Toxic Shock Syndrome). 8th edition. Philadelphia: Elsevier; 2015

Ruoff KL, Bisno AL in Bennet JE, Dolin R, Blaser MJ. Principles and Practice of Infectious Disease: Classification of Streptococci. 8th edition. Philadelphia: Elsevier; 2015

Sinner SW, Tunkel AR in Bennet JE, Dolin R, Blaser MJ. Principles and Practice of Infectious Disease: Viridans Streptococci, Nutritionally Variant Streptococci, Groups C and G Streptococci, and Other Related Organisms. 8th edition. Philadelphia: Elsevier; 2015

Hauser AR. Antibiotic Basics for Clinicians. Second Edition. Philadelphia: Lippincolt Williams & Wilkins; 2013

Tadesse DA, Zhao S, Kumar A in Mahon CR, Lehman DC, Manuselis G. Textbook of Diagnostic Microbiology: Antimicrobial Agent Mechanisms of Action and Resistance. Fifth edition. United States: Saunders; 2015

Cauwelier B, Gordts B, Descheemaecker P, Landuyt HV. Evaluation of a disk diffusion method with cefoxitin (30 μg) for detection of methicillin-resistant Staphylococcus aureus. European Journal of Clinical Microbiology and Infectious Diseases. May 2004. 23(5): 389-392




DOI: https://doi.org/10.33508/jwm.v7i2.3307